Honolulu, HI

mcarbone@cc.hawaii.edu

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s2-2024

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research HMGB1 Research Findings Therapeutic Approaches

14 Jul: Germline BARD1 Mutations Predispose to Mesothelioma by Impairing DNA Repair and Calcium Signaling

Ca: A Cancer Journal for Clinicians 2019

Asbestos-Risk-Assessment-Epidemiology

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings Therapeutic Approaches

14 Jul: Asbestos: Risk Assessment, Epidemiology, and Health Effects

Translational Lung Cancer Research: Focused Issue

does-asbestos-ban-reduce-mesothelioma-incidence

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

23 May: Did the Ban on Asbestos Reduce the Incidence of Mesothelioma?

Journal of Thoracic Oncology 2023

bap1-hif-1a

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

25 Mar: BAP1 is a novel regulator of HIF-1α

The Proceedings of the National Academy of Sciences in the USA 2023

bap1-trimer-hmgb1-hdac1

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

25 Mar: BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos

The Proceedings of the National Academy of Sciences in the USA 2021

Nature image

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

10 May: BAP1 Regulates IP3R3-mediated Ca2+ Flux to Mitochondria Suppressing Cell Transformation

Nature: Cell Death and Disease 2017

Michele Carbone, MD, PhD

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Gene X Interaction Genetic Research Research Findings

02 Jun: Tumour Predisposition and Cancer Syndromes as Models to Study Gene–Environment Interactions

Nature Reviews Cancer 2020

translational-lung-cancer-research

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings Therapeutic Approaches

15 Apr: Mesothelioma: What We Know and What We Do Not Know in 2020

Translational Lung Cancer Research: Focused Issue

Image-7-9-19-at-10.20-AM

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research HMGB1 Research Findings Therapeutic Approaches

10 Jul: Mesothelioma: Scientific Clues for Prevention, Diagnosis, and Therapy

Ca: A Cancer Journal for Clinicians 2019

41419_2018_1206_Fig1

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By Oak Park Pathology BAP1 Syndrome Genetic Research Research Findings

12 Dec: BAP1 Regulates Different Mechanisms of Cell Death

Nature 2018

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