On November 9 and 10, 2015, the International Conference on Mesothelioma in Populations Exposed to Naturally Occurring Asbestiform Fibers was held at the University of Hawaii Cancer Center in Honolulu, Hawaii. The meeting was cosponsored by the International Association for the Study of Lung Cancer, and the agenda was designed with significant input from staff at the U.S. National Cancer Institute and National Institute of Environmental Health Sciences.
A multidisciplinary group of participants presented updates reflecting a range of disciplinary perspectives, including mineralogy, geology, epidemiology, toxicology, biochemistry, molecular biology, genetics, public health, and clinical oncology. The group identified knowledge gaps that are barriers to preventing and treating malignant mesothelioma (MM) and the required next steps to address barriers.
This manuscript reports the group’s efforts and focus on strategies to limit risk to the population and reduce the incidence of MM. Four main topics were explored:
- Genetic risk
- Environmental exposure
- Clinical interventions
Authors: Michele Carbone, MD, PhD, Shreya Kanodia, PhD, Ann Chao, PhD, Aubrey Miller, MD, Anil Wali, PhD, David Weissman, MD, Alex Adjei, MD, PhD, Francine Baumann, PhD, Paolo Boffetta, MD, PhD, Brenda Buck, PhD, Marc de Perrot, MD, A. Umran Dogan, PhD, Steve Gavett, PhD, Alessandro Gualtieri, PhD, Raffit Hassan, MD, Mary Hesdorffer, NP, Fred R. Hirsch, MD, PhD, David Larson, PhD, Weimin Mao, PhD, Scott Masten, PhD, Harvey I. Pass, PhD, Julian Peto, DSc, Enrico Pira, Phd, Ian Steele, MD, Anne Tsao, MD, Gavitt Alida Woodard, MD, Haining Yang, PhD, Shakun Malik, MD