Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma
CFI-402257 is a promising novel therapeutic agent to improve the efficacy of the current chemotherapeutic regimens for MM patients.
published in Translational Lung Cancer Research, June 16, 2017
A review of the most promising biomarkers for early detection of malignant mesothelioma.
A Review of our Projects, Publications, and Discoveries
Annals of Translational Medicine 2017: Review Article
Recent discoveries have elucidated some of the mechanisms responsible for the development of mesothelioma.
We studied the effect of ethyl pyruvate (EP), the ethyl ester of pyruvic acid, on the malignant phenotype of MM cells in tissue culture and on tumor growth in vivo using an orthotopic MM xenograft model.