For the past 10 years, the Virginia & Barry Weinman Foundation, in conjunction with the University of Hawaii Cancer Center, has sponsored an annual meeting of top researchers from around the world. This publication in Cell Death & Differentiation (6 August 2018) is a consensus report about the role of genes and environment in carcinogenesis.
Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma
CFI-402257 is a promising novel therapeutic agent to improve the efficacy of the current chemotherapeutic regimens for MM patients.
Cell Death and Differentiation, June 30, 2017 (doi: 10.1038/cdd.2017.95)
Aerobic glycolysis, also known as the ‘Warburg effect’, does not necessarily occur as an adaptive process that is consequence of carcinogenesis, but rather that it may also predate malignancy by many years and facilitate carcinogenesis.
published in Translational Lung Cancer Research, June 16, 2017
A review of the most promising biomarkers for early detection of malignant mesothelioma.
Nature International Weekly Journal of Science (2017) - doi:10.1038/nature22798
A mechanistic rationale for the ability of BAP1 to regulate gene-environment interaction in human carcinogenesis