Dr. Carbone's research work posited and later proved that gene/environment interactions cause Malignant Mesothelioma and other types of cancers. The goal of his research is to develop effective preventive strategies for Malignant Mesothelioma and increase early diagnosis and long-term survivors among patients.
Dr. Carbone has led multi-national, interdisciplinary teams to remote areas of the United States and Europe to investigate how the presence of mineral fibers such as asbestos and erionite affect human populations. This work has demonstrated that development activities around the world have increased the incidence of Malignant Mesothelioma.
Dr. Carbone’s team studies the biological mechanisms that are associated with the development of Malignant Mesothelioma so that simple, non-invasive blood and/or saliva tests can provide identification of patients in the early stages of the disease. When Malignant Mesothelioma is discovered earlier, lives can be prolonged.
Drs. Carbone and Yang with their team at the UH Cancer Center.
Dr. Carbone has devoted much of his research career to the investigation of the causes and possible cures for Malignant Mesothelioma, a deadly cancer that affects between 3,000 - 5,000 people annually in the United States and Europe. His research has been published in many peer-reviewed scientific journals, and his laboratory is funded by grants from the National Cancer Institute as well as other non-profit cancer research organizations. His work has been cited over 10,000 times.You can access a list of his scientific publications in Google Scholar. Here are links to lay and peer press coverage of his work:
National Cancer Institute Grant 1R01CA198138-01), $1,922,500.00 total cost awarded 07/01/2015, ends 06/30/2020. Role: Principal Investigator.
V Foundation, $180,000 annual direct costs, awarded 10/31/2012, ends 10/30/2016. Role: Co-investigator with H. Yang.
DoD Peer Reviewed Cancer Research Program Idea Award with Special Focus Department of Defense. $400,000 total direct cost, awarded 10/01/2016, ends 10/31/2018. Role Co-investigator with H. Yang.
DoD Peer Reviewed Cancer Research Program Translational Team Science Award Department of Defense award, total direct cost $1,200,000, awarded 07/01/2016, ends 06/30/2019; Role – Co-investigator with H. Yang, H. Pass, T. Mak,S. Kanodia
UH Foundation received unrestricted gifts to support Michele Carbone's research on malignant mesothelioma from:
Dr. Carbone's research in mesothelioma has been continuously funded through the National Institutes of Health, the National Cancer Institute, the American Association for Cancer Research, and other private and public grants. Since 1989, he has authored or co-authored over 200 publications.
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